# How do Children’s Zyrtec liquid, chewables and Dissolve Tabs differ?

Canonical URL: https://kintoolkit.com/questions/childrens-zyrtec-liquid-chewable-dissolve-tabs

Children’s Zyrtec allergy products contain cetirizine HCl, but the liquid, 2.5 mg chewable, 10 mg chewable and 10 mg Dissolve Tabs have separate directions. Match the exact package; this comparison is not a conversion or substitution chart.

## Products in this guide

| Product | Form | Ingredient | Printed strength | References |
| --- | --- | --- | --- | --- |
| Children’s ZYRTEC | Syrup | Cetirizine HCl | 1 mg / mL | [Enlarge label](https://kintoolkit.com/bottles/childrens-zyrtec-bottle-display-1400.webp) · [Dosage chart](https://kintoolkit.com/cetirizine-pediatric-dose-calculator#label-charts) · [Manufacturer guidance](https://www.zyrtec.com/products/zyrtec-dosage-guide) |
| Children’s Zyrtec | Grape chewable | Cetirizine HCl | 2.5 mg / tablet | [Enlarge label](https://kintoolkit.com/products/zyrtec-2-5-mg-chewable.webp) · [Product guide](https://kintoolkit.com/questions/childrens-zyrtec-2-5-mg-chewable-label) · [Manufacturer guidance](https://www.zyrtec.com/products/zyrtec-chewables-children-2-plus) |
| Children’s Zyrtec | Grape chewable | Cetirizine HCl | 10 mg / tablet | [Enlarge label](https://kintoolkit.com/products/zyrtec-10-mg-chewable.webp) · [Product guide](https://kintoolkit.com/questions/childrens-zyrtec-liquid-chewable-dissolve-tabs#section-3) · [Manufacturer guidance](https://www.zyrtec.com/products/zyrtec-chewables-children-6-plus) |
| Children’s Zyrtec | Citrus Dissolve Tabs | Cetirizine HCl | 10 mg / tablet | [Enlarge label](https://kintoolkit.com/products/zyrtec-dissolve-tabs.webp) · [Product guide](https://kintoolkit.com/questions/childrens-zyrtec-liquid-chewable-dissolve-tabs#section-4) · [Manufacturer guidance](https://www.zyrtec.com/products/zyrtec-children-dissolve-tabs) |

## Allergy syrup: 1 mg/mL

The grape US Children’s Zyrtec Allergy syrup contains 5 mg per 5 mL (1 mg/mL). Example package: NDC 50580-730-05, 118 mL. The DailyMed record was updated October 10, 2025. Use the enclosed dosing cup. Its pediatric directions begin at age 2; for children under 2, ask a doctor.

- [Syrup Drug Facts on DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9d8e78ea-af98-4f7c-8db5-044b49582f80)
- [ZYRTEC syrup manufacturer guidance](https://www.zyrtec.com/products/zyrtec-children-allergy-syrup)
- [Supported syrup label lookup](https://kintoolkit.com/cetirizine-pediatric-dose-calculator)

## Grape chewables: 2.5 mg per tablet

The 2.5 mg chewable has directions for ages 2 to under 6 and for older users. Under age 2, ask a doctor. Chew or crush completely before swallowing; water is optional. Example package: NDC 50580-790-01, 12 tablets. DailyMed updated April 7, 2025.

- [Read the complete direction groups for 2.5 mg chewables](https://kintoolkit.com/questions/childrens-zyrtec-2-5-mg-chewable-label)
- [2.5 mg chewable Drug Facts](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=013ce40e-37c9-4b84-b530-ed895f60ce0e)
- [ZYRTEC 2.5 mg manufacturer guidance](https://www.zyrtec.com/products/zyrtec-chewables-children-2-plus)

## Grape chewables: 10 mg per tablet

The 10 mg chewable is a different strength, with directions starting at age 6. Under age 6, ask a doctor. Chew or crush completely before swallowing; water is optional. The DailyMed record, updated April 22, 2026, lists NDC family 50580-791. Do not transfer the 2.5 mg tablet count to this product.

- [10 mg chewable Drug Facts](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0fe77356-d945-46a0-882e-b3bbab784556)
- [ZYRTEC 10 mg chewable manufacturer guidance](https://www.zyrtec.com/products/zyrtec-chewables-children-6-plus)

## Citrus Dissolve Tabs: 10 mg per tablet

This orally disintegrating tablet melts in the mouth, with water optional. Its directions start at age 6; under age 6, ask a doctor. Example package: NDC 50580-782-12, 12 tablets. DailyMed updated April 22, 2025. A mention of a lower-strength product in a label does not establish instructions to split a 10 mg tablet.

- [Dissolve Tabs Drug Facts](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a1edc2e6-3661-4d7a-884c-709d73cb89e0)
- [ZYRTEC Dissolve Tabs manufacturer guidance](https://www.zyrtec.com/products/zyrtec-children-dissolve-tabs)

## Read each product’s full warnings

These are allergy formulations, not Children’s Zyrtec Hives Relief or combination products. Matching ingredient does not establish that products can be combined or substituted. Check the actual package and ask a pharmacist about differences before use. Only the syrup is supported by KinToolkit’s calculator.

Cetirizine warnings include drowsiness and precautions with alcohol or sedating medicines. The FDA also warns about rare severe itching after stopping long-term cetirizine use. Ask a healthcare professional about this risk; this page supplies no stopping or tapering schedule.

- [FDA: itching after stopping cetirizine](https://www.fda.gov/drugs/drug-safety-communications/fda-requires-warning-about-rare-severe-itching-after-stopping-long-term-use-oral-allergy-medicines)
- [Age versus weight for Zyrtec syrup](https://kintoolkit.com/questions/childrens-zyrtec-dose-age-or-weight)
- [Claritin liquid is a different ingredient](https://kintoolkit.com/questions/childrens-claritin-liquid-label)

## Related questions



- [What does the Children’s Zyrtec 2.5 mg chewable label say?](https://kintoolkit.com/questions/childrens-zyrtec-2-5-mg-chewable-label)
- [Can I calculate children’s cetirizine dosage in mg/kg?](https://kintoolkit.com/questions/childrens-cetirizine-mg-per-kg)
- [Bottle and dosage chart don’t match?](https://kintoolkit.com/questions/medicine-bottle-online-chart-disagree)

## About these references

These are educational references for the exact US products shown, not personalized prescriptions or clinically reviewed dosing protocols. Read your package’s full Drug Facts. Product guides do not expand the bottles supported by the calculators.

Sources checked and page updated: 2026-10-21. This records source verification, not clinical review.

- [How KinToolkit prepares references](https://kintoolkit.com/about)

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